Mane, who won the last award in 2019, will be favoured to win again after a season in which he helped Senegal to their first Africa Cup of Nations title plus qualification to the World Cup in Qatar.
He also had cup success with Liverpool at club level, lifting the FA Cup and Carabao Cup, and has since moved to Bayern Munich.
Liverpool has another contender in the shape of Naby Keita, whilst Manchester City have Riyad Mahrez in contention.
Salah won the award in 2017 and 2018 and Mahrez in 2016.
The COVID-19 pandemic and decision to switch the qualification period from the calendar year to the 2021-22 season is the reason why there has been no award for the last three years, CAF officials told Reuters.
The winner will be decided by a judging panel made up of members of CAF’s technical committee, press and coaches and captains of Africa’s 54 national teams and will be announced at a ceremony in Rabat, Morocco on July 21.
Nominees: Vincent Aboubacar (Cameroon), Achraf Hakimi (Morocco), Sebastien Haller (Ivory Coast), Naby Keita (Guinea), Kalidou Koulibaly (Senegal), Riyad Mahrez (Algeria), Sadio Mane, Edouard Mendy (both Senegal), Mohamed Salah (Egypt), Karl Toko Ekambi (Cameroon).