The Gunners saw off Norwegian champions Bodo/Glimt 3-0 at the Emirates Stadium courtesy of first-half goals from Eddie Nketiah and Rob Holding.
Fabio Vieira struck in the second-half, six minutes from time, to round off the result.
The Gunners are top of Group A after back-to-back wins. Their clash with PSV Eindhoven last month was rescheduled following the death of Queen Elizabeth II.
Elsewhere, on-loan Arsenal forward Nicolas Pepe got the only goal for Nice in a 1-0 victory away to Czech outfit Slovacko.
