Denis Zakaria scored the winner on his Chelsea debut as the Blues came from behind to beat the Croatian champions.
But the night ended on a sour note for Chelsea and England when Chilwell had to be helped off the field in stoppage time to seemingly spoil his hopes of going to Qatar.
"It doesn't look positive. It's a hamstring, said Chelsea boss Graham Potter. "We will have to scan it and see how it is."
Chilwell, who has 17 caps for the Three Lions, was part of the England squad that reached the final of Euro 2020.
England open their campaign against Iran in less than three weeks on November 21st.
