Take a look at who's out and who's questionable with our guide below.

Crystal Palace vs Brighton - Thursday 21:00 CET

Crystal Palace

WON'T PLAY:

Doucoure C. (Achilles Tendon Injury)

Edouard O. (Knee Injury)

Holding R. (Ankle Injury)

Johnstone S. (Calf Injury)

Rak-Sakyi J. (Thigh Injury)

Ward J. (Thigh Injury)

Brighton

WON'T PLAY:

Enciso J. (Knee Injury)

Estupinan P. (Injury)

Fati A. (Calf Injury)

Lamptey T. (Muscle Injury)

March S. (Knee Injury)

Veltman J. (Knee Injury)

Webster A. (Knock)

QUESTIONABLE:

Lerma J. (Thigh Injury)

Aston Villa vs Sheffield United - Friday 21:00 CET

Aston Villa

WON'T PLAY:

Buendia E. (Knee Injury)

Kamara B. (Red Card)

Mings T. (Knee Injury)

Traore B. (Muscle Injury)

Sheffield United

WON'T PLAY:

Basham C. (Ankle Injury)

Brewster R. (Thigh Injury)

Davies T. (Injury)

Egan J. (Ankle Injury)

Jebbison D. (Muscle Injury)

Norrington-Davies R. (Muscle Injury)

QUESTIONABLE:

Tielemans Y. (Knock)

Torres P. (Injury)

West Ham vs Manchester United - Saturday 13:30 CET

West Ham

WON'T PLAY:

Antonio M. (Knee Injury)

Man Utd

WON'T PLAY:

Casemiro (Hamstring Injury)

Dalot D. (Red Card)

Diallo A. (Knee Injury)

Eriksen C. (Knee Injury)

Maguire H. (Groin Injury)

Malacia T. (Muscle Injury)

Martinez Li. (Foot Injury)

Mount M. (Injury)

Sancho J. (Coach's decision)

QUESTIONABLE:

Lindelof V. (Knock)

Martial A. (Illness)

Fulham vs Burnley - Saturday 16:00 CET

Fulham

WON'T PLAY:

Jimenez R. (Red Card)

Traore A. (Thigh Injury)

Burnley

WON'T PLAY:

Koleosho L. (Knee Injury)

QUESTIONABLE:

Ream T. (Calf Injury)

Cork J. (Injury)

Ramsey A. (Knee Injury)

Luton vs Newcastle - Saturday 16:00 CET

Luton

WON'T PLAY:

Burke R. (Injury)

Lockyer T. (Heart Problems)

Potts D. (Ankle Injury)

Newcastle

WON'T PLAY:

Anderson E. (Back Injury)

Barnes H. (Ankle Injury)

Joelinton (Muscle Injury)

Manquillo J. (Groin Injury)

Murphy J. (Shoulder Injury)

Pope N. (Shoulder Injury)

Schar F. (Muscle Injury)

Targett M. (Injury)

Tonali S. (Suspended)

Willock J. (Achilles Tendon Injury)

QUESTIONABLE:

Woodrow C. (Calf Injury)

Isak A. (Groin Injury)

Nottingham Forest vs Bournemouth - Saturday 16:00 CET

Nottingham Forest

WON'T PLAY:

Aurier S. (Calf Injury)

Awoniyi T. (Groin Injury)

Felipe (Muscle Injury)

Bournemouth

WON'T PLAY:

Aarons M. (Thigh Injury)

Adams T. (Thigh Injury)

Fredericks R. (Calf Injury)

Kelly L. (Thigh Injury)

Marcondes E. (Ankle Injury)

Traore H. J. (Illness)

QUESTIONABLE:

Randolph D. (Illness)

Tottenham vs Everton - Saturday 16:00 CET

Tottenham

WON'T PLAY:

Bentancur R. (Ankle Injury)

Maddison J. (Ankle Injury)

Perisic I. (Knee Injury)

Sessegnon R. (Thigh Injury)

Solomon M. (Knee Injury)

Udogie D. (Yellow Cards)

Whiteman A. (Ankle Injury)

van de Ven M. (Thigh Injury)

Everton

WON'T PLAY:

Alli D. (Muscle Injury)

QUESTIONABLE:

Lo Celso G. (Injury)

Coleman S. (Injury)

Doucoure A. (Thigh Injury)

Gomes A. (Injury)

Mykolenko V. (Injury)

Young A. (Injury)

Liverpool vs Arsenal - Saturday 18:30 CET

Liverpool

WON'T PLAY:

Bajcetic S. (Calf Injury)

Diogo Jota (Muscle Injury)

Mac Allister A. (Knee Injury)

Matip J. (Knee Injury)

Robertson A. (Shoulder Injury)

Thiago (Hip Injury)

Arsenal

WON'T PLAY:

Partey T. (Muscle Injury)

Timber J. (Knee Injury)

Tomiyasu T. (Calf Injury)

Vieira F. (Groin Injury)

QUESTIONABLE:

Gravenberch R. (Thigh Injury)

Elneny M. (Thigh Injury)

Jorginho (Foot Injury)

Wolves vs Chelsea - Christmas Eve 14:00 CET

Wolves

WON'T PLAY: TBC

Chelsea

WON'T PLAY: TBC

QUESTIONABLE: TBC