A star-studded field of eight established champions and potential spoilers will battle for a place in the semi-finals and subsequent final, hoping to etch their name into the sport's history books.
The tournament saw a record number of seeds tumble during the earlier rounds, with the likes of former champions Michael Smith, Rob Cross and Gary Anderson falling at their first hurdles in the second round.
The defending champion - favourite for many to retain his crown - also suffered a shock defeat in the last 16 to a resurgent Peter Wright.
Here's a look at the state of play in the PDC World Darts Championship going into the business end of the tournament:
Chris Dobey (15) v Gerwyn Price (10)
'Hollywood' Chris Dobey defeated Kevin Doets 4-3 with a thrilling 98.73 average and five 180s in the previous round.
He'll need to maintain his scoring power and limit mistakes against the experienced Price, who has comfortably won the previous 12 encounters between the pair.
The 'Iceman' defeated compatriot Jonny Clayton 4-2 with a 99.17 average in the last 16 and overcame a stiff challenge from world number 23 Joe Cullen prior.
He's averaging 92.29 for the tournament, just shy of Dobey's 94.39.
The winner will face either Michael van Gerwen or Callan Rydz in the semi-final.
Michael van Gerwen (3) v Callan Rydz
Three-time champion Van Gerwen cruised past Jeffrey de Graaf 4-2 in the third round with a decent 101.98 average, hitting 21 180s and finishing 44 per cent on the doubles.
He boasts an impressive six ton-plus checkouts for the tournament - two ahead of his nearest rivals.
Young Englishman Rydz produced a stunning upset over Robert Owen in the last 16 to reach the quarter-finals. The lowest-ranked player left in the tournament at 43, his record against MVG actually isn't too bad, with the 26-year-old winning two out of the previous five meetings against the world number three.
Rydz is averaging 99.43 for the tournament, one behind Littler for the overall lead. He'll need to maintain his aggressive style and limit mistakes - and perhaps hope an improving Van Gerwen has a wobble at the oche.
Peter Wright (17) v Stephen Bunting (8)
The flamboyant Peter Wright humbled the defending world champion and number one ranked Luke Humphries 4-1 in a thrilling encounter in the last 16, averaging 100.93 (95.87 for the tournament). A dangerous-looking 'Snakebite' has been rolling back the years, hitting 19 180s and a tournament-best 52 per cent checkout rate so far at Ally Pally.
The two-time former world champion looks to have rediscovered his form at the perfect time as he makes a surprise - and suddenly very realistic - tilt at a third title.
"If I didn't beat him in this round, I believe he would have retained his title, because I don't think any other player would have got close to Luke over a longer distance," Wright told the PDC after stunning Humphries.
"Humphries and Littler inspire me to carry on playing darts, and I know I can still play this game.
"I felt like I struggled throughout the whole game tonight. I'm over the moon with the result, but I know I can get better."
Eighth seed Stephen Bunting whitewashed Luke Woodhouse in the last round with a convincing 96.78 average, six one 180s, and an astonishing 40 ton-plus visits.
His experience on the big stage and clinical finishing will be crucial against the unpredictable Wright, and he'll see this as a glittering opportunity to earn his first world championship after tasting disappointment early door last year.
It's generally the Scotsman who gets the better of the Liverpudlian, with Wright winning the previous two meetings, but Bunting has had his fair share of victories as well, particularly in the three matches before those.
The winner will face either Luke Littler or Nathan Aspinall in the semis.
Luke Littler (4) v Nathan Aspinall (12)
Main attraction Luke Littler produced a thrilling comeback against Ryan Joyce in the last 16. The world number four was pushed all the way as Joyce took three sets in what was ultimately a losing effort, with 'the Nuke' eventually coming out on top in a 4-3 victory.
The 17-year-old averaged 103.14 and hit an eye-catching 14 180s, but struggled to finish off his opponent and missed several doubles with a highest checkout of just 68.
Still, he came out on top and the bookies' favourite leads the tournament's overall average (100.88) and 180-count (36, 10 ahead of Rydz in second).
His finishing hasn't been the best though, trudging in at 38 per cent, better than only Gerwyn Price and Chris Dobey.
He's going up against his old mate Nathan Aspinall, who he's beaten on the last five straight occasions.
"I'm expecting Nathan to play very well," Littler said after beating Joyce.
"We've played each other many times before, we know how we can play.
"This is the quarter-final of the World Championship, so may the best man win on the day!"
The 'Asp' hammered Ricardo Pietreczko 4-0 with a 94.28 average and six 180s (15 for the tournament).
The 33-year-old's finishing is looking good at 47 per cent, and he's recorded three ton-plus checkouts along the way. Aspinall a former World Grand Prix champion, will fancy his chances against a Littler who looks yet to hit full stride.
