A day after throwing cold water over British hopes by out-lasting Andy Murray in a five-set cliffhanger spanning two days on Centre Court, he returned to dispatch Serbia's Djere in more straightforward fashion, winning 6-4 7-6(5) 6-4.
His energy levels looked undiminished despite it being his fifth successive day on court, a shift that began with a first-round five-setter against former U.S. Open champion Dominic Thiem -- a match that took two days to complete.
His clash with Murray, where he battled the two-time Wimbledon champion and the 15,000 fans for nearly five hours, was the longest match in the tournament so far.
He has spent eight hours and 46 minutes on court and a more relaxing Sunday is well-earned.
After that he will focus on his fourth round match against unseeded American Christopher Eubanks who continued his impressive run on grass with victory over Christopher O'Connell on Saturday.
Tsitsipas pocketed the first set when Djere faltered serving at 4-5, double-faulting on set point.
He found himself a break down in the second set but once he repaired that damage and took the tiebreak it was relatively smooth for the elegant Greek shot-maker.
