Shortly after Kyrgios completed a brilliant victory over world number one and 2021 champion Daniil Medvedev at the Arthur Ashe Stadium, Tomljanovic backed up her win over retiring Serena Williams (40) with a 7-6(8) 6-1 triumph at the neighbouring Louis Armstrong Stadium.

Samsonova came into the evening contest against Tomljanovic on a 13-match winning streak, having lifted titles in Cleveland and Washington DC in the leadup to the hardcourt Grand Slam at Flushing Meadows.

The Russian peppered the court with winners and quickly stacked up a 5-2 lead in the opening set.

Tomljanovic showed a lot of resilience to save seven set points and hold serve during a 14-minute marathon ninth game and then successfully defended another setpoint during the tiebreaker to take the opening frame.

The missed opportunities seemed to take a toll on Samsonova's confidence as her errors mounted and Tomljanovic raced through the second set with two breaks of serves to reach the quarter-finals at a major for the third time.

Tomljanovic, who reached the Wimbledon's last-eight stage for the previous two editions, will next face Tunisian fifth seed Ons Jabeur (28) after she defeated the 18th seeded Russian Veronika Kudermetova (25).

"I think my will to go further in this tournament was really strong and I didn't want to stop just after what happened on Friday night," she said.

"I thought I deserved more. I definitely wanted to go for more. I dug deep because I felt like I had more left in me."