Bjorn has represented Europe three times as a player, six times as vice-captain and captained the team to victory in the 2018 edition in Paris.
He is the second vice-captain to be named by Donald following Italian Edoardo Molinari (43).
"He means a lot to me. He's passed on his knowledge and I've had a great relationship with him over the last few years. To have those relationships, to enjoy the people you're spending time with along that journey is really important," Donald said in a statement.
"This is an away Ryder Cup, so the earlier we can start planning, the better...
"Now I have Edoardo and Thomas alongside me I can get together with them and start the planning process around how we can create the right culture for the team to succeed in New York."
The biennial contest will be held in Bethpage Black from September 26th-28th, 2025.
