Mikaela Shiffrin led the field after the first run of the season closing World Cup giant slalom at Andorra on Sunday.
Last out of the gate the American sped through the 39 turning gates in 56.60sec to push Canadian Valerie Grenier into second at 0.62sec with Italy's Marta Bassino in thrid.
In bright sunshine with temperatures at 3C the skiing conditions were perfect for the 330m vertical drop on hard snow from a 2167m altitude starters gate.
Three of the pre-race favourites bombed out in the first run as the Slovak Petra Vlhova, Sweden's Olympic champion Sara Hector and Italy's Federica Brignone all plunged through gates.
Should the 28-year-old from Colorado retain her handsome lead through the second run she will claim a record 88th career win and a 14th of the season.
Shiffrin secured her fifth overall crystal globe two weeks ago.
