"And with that I say goodbye to the 2023 season!" Lyles said in a post on X, formerly known as Twitter.
The social media post included three checked boxes: "World's fastest man in 100 & 200; 2 years undefeated in the 200m; 3X world champion."
The news means Lyles, arguably the US team's biggest name, will not race at home in the Diamond League final on September 16th-17th in Eugene.
Lyles closed his season with a victory in the 200 at the Weltklasse Diamond League meeting on Thursday in Zurich and tops the 200m standings with wins in all three of his appearances.
The Diamond League circuit has two stops before the final, on Saturday at Xiamen, China and the Memorial Van Damme, September 8th-9th in Brussels.
In one of the major highlights of the Budapest World Championships, Lyles captured gold in the 100, 200 and 4x100 relay, becoming the first man to achieve the feat since Jamaican Usain Bolt in 2015.
Next year's Paris Olympics are almost three weeks earlier than the worlds were this year, with athletics scheduled for August 1st-11th.
