Just seven days after Tsitsipas thumped Ruud in straight sets to win the Monte Carlo Masters, it was the Danish third seed who came out on top in the latest battle between the two 25-year-olds as he secured a 10th ATP title on clay.
"Honestly, this has been worth the wait," Ruud said after capturing the biggest title his career, with all his previous triumphs being in ATP 250 tournaments.
After seven failed attempts to win a final above the ATP 250 level, Ruud was relieved to finally get over that hurdle.
"A lot of finals that I've lost have been tough, a bit disappointing, of course," he said.
"Any time you reach a final, it's nonetheless a good week, so you can’t be too hard on yourself but this one has been a long time coming."
Ruud also halted Tsitsipas' 10-match winning streak.
The Greek gained an early break but Ruud soon got into his groove and from then on he frustrated Tsitsipas with his baseline tactics.
Ruud maintained the upper hand throughout the second set, during which he did not face a break point.
"In the final in Monte Carlo I was always on the back foot, too far behind, and he had too much time to control the game," Ruud said.
"It was a bit of a tricky start (here), I got broken right away. So not the best start, but I managed to settle in and broke him back."
The world number six will hope the win will boost his chances of finally winning the biggest prize in claycourt tennis, following his runner-up finishes to Rafael Nadal and Novak Djokovic at the French Open over the past two years.
