The Serbian world number one owns a joint record six Miami Open titles but was unable to even attempt adding to that tally in recent years as the United States did not allow unvaccinated foreigners to enter the country.
Reigning champion Daniil Medvedev and 2023 finalist Jannik Sinner are also on the entry list, with the latter having since avenged that loss when he beat the Russian in the Australian Open final to become the first Italian man to win a Grand Slam title since 1976.
Among the other names in the men's field are Spain's Carlos Alcaraz while Americans Taylor Fritz, Tommy Paul, Frances Tiafoe and Ben Shelton will lead the home charge.
On the women's side, world number one Iga Swiatek will be seeking a second Miami Open title, having previously triumphed in 2022 when she beat four-time Grand Slam winner Naomi Osaka in the final.
World number two Aryna Sabalenka, who retained her Australian Open title this year without dropping a set, and Florida residents Coco Gauff, Jessica Pegula and Madison Keys are all also expected to be in the women's field.
Defending women's champion Petra Kvitova is not playing this year, having announced her pregnancy at the start of the year.
This year's Miami Open is scheduled for March 17th to 31st.
