Lockyer collapsed during Luton's promotion play-off final win at Wembley against Coventry City on May 27th. The club captain spent five days in hospital and had an operation to fix an atrial fibrilation.
He returned for pre-season training at Luton after receiving the all-clear. He has played in the club's two Premier League games so far this season, and in their League Cup win over Gillingham on Tuesday.
"It's a great story. We all watched the events unfold in the playoff final. We were all concerned, but there has been nothing but positivity since that day," Wales manager Rob Page (48) told reporters at the squad announcement.
"He has had some great news, he is back to normal and is now playing in the Premier League, which is unbelievable for him as well."
Lockyer was named in the Wales squad for last year's Qatar World Cup and for their two Euro 2024 qualifiers in March. He, however, missed two recent qualifiers in which Wales lost to Armenia and Turkey.
Wales play South Korea in a friendly on September 7th before travelling to Latvia for a Euro qualifier on September 11th.
Page has named a 25-man squad for both fixtures and has included three uncapped players, Tom King (28), Morgan Fox (29) and Liam Cullen (24).
